專業:生物學 研究方向:生物化學與分子生物學、計算機輔助藥物設計 主持項目: (1)國家級人才項目--環境科學與技術(2014.06-2018.06) (2)山東省自然科學基金面上--含氯離去基團Pt(IV)抗腫瘤復合物與生物分子相互作用理論研究(2019.7-2022.6) (3)山東省教育基金--高端人才團隊建設費(2018.4-2023.3) (4)中科院人才專項--稀土貴金屬催化劑用于汽車尾氣氮氧化物凈化的計算機模擬研究 (2015.01-2018.06) (5)新疆維吾爾自治區自然科學基金--新疆稀土礦應用于機動車尾氣凈化的計算機模擬研究(2017.1-2018.07) (6)浙江省自然科學基金--稀土鈣鈦礦型氧化物用于汽車尾氣催化凈化的計算機模擬研究(2009.01-2010.12) 代表性論文: (1)Yingying Jiang,Hongwei Gao*,Pharmacophore-based drug design for the identification of novel butyrylcholinesterase inhibitors against Alzheimer's disease,Phytomedicine,2019,54, 278-290. (2)Yingni Sun*?, Lisheng Liang?, Meili Dong, Cong Li, Zhenzhen Liu andHongwei Gao*, Cofilin 2 in Serum as a Novel Biomarker for Alzheimer’s Disease in Han Chinese,Frontiers in Aging Neuroscience,2019, 00214: 1-11. (3)Hongwei Gao*,Predicting tyrosinase inhibition by 3D QSAR pharmacophore models and designing potential tyrosinase inhibitors from Traditional Chinese Medicine Database,Phytomedicine,2018,38, 145-157. (4) Gulmira Turdu, Yingying Jiang, Madina Kabas,Azizullo Musoev,Hongwei Gao*, Dipeptidyl peptidase-IV inhibitors as anti-diabetic agents – A brief review,Future Medicinal Chemistry,2018,10(10): 1229-1239. (5)Yingying Jiang,Hongwei Gao*, Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database,Bioorganic Chemistry,2018,76, 400-414. (6)Yue Yang,Hongwei Gao*, Density functional theory study on the molecular structure and vibration spectra of fenbufen,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2013,101, 119-126. (7)Lekun Liu,Hongwei Gao*, Zhaozhe Cui, Molecular structure and vibrational spectra studies on antipyrine derivative, 4-(2,3,4-trihydroxybenzylideneamino) antipyrine,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2013,112, 191-197. (8)Yue Yang,Hongwei Gao*, Comparison of DFT methods for molecular structure and vibration spectra of ofloxacin calculations,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2012,85, 303-309. 獲獎情況: (1)浙江省高等學校科研成果獎,二等獎,1/5(排名),(2010.12) 榮譽稱號: (1)國家級特聘專家, 1/1(排名),(2014.7) (2)浙江省“新世紀151人才工程”, 1/1(排名),(2009.8) (3)溫州市“新世紀551人才工程” , 1/1(排名),(2010.11) (4)溫州市優秀科技特派員, 1/1(排名),(2011.2) (5)溫州醫科大學第二批校級中青年學科帶頭人, 1/1(排名),(2010.10) (6)魯東大學高層次A類人才,1/1(排名),(2018.9) |